Primary biliary cholangitis (PBC) is an autoimmune disorder that affects the bile ducts in the liver, leading to inflammation and, eventually, advanced liver disease. The introduction of ursodeoxycholic acid (UDCA) in 1997 significantly altered the management landscape for PBC, offering patients a tangible option for mitigating the progression of their disease. Nevertheless, despite the promising
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As human beings, the desire to live longer intertwines deeply with the aspiration to live healthily. In the last hundred years, life expectancy has seen a remarkable rise due to factors such as improved sanitation, advancements in public health, better nutrition, and significant medical breakthroughs. For instance, Statistics Canada reports that in 2021, the average
In a shocking development that has reverberated throughout the Middle East, insurgent forces have reinitiated combat operations in Aleppo, Syria’s largest city, marking the first significant clashes with government troops since 2016. This escalation has not only unsettled the residents of Aleppo, sending many fleeing their homes, but it has also raised alarming questions about
In a significant development that underscores the tensions between digital innovation and traditional media rights, five prominent Canadian news organizations initiated legal proceedings against OpenAI on Friday. This lawsuit signals a growing wave of actions taken by journalists, artists, and other stakeholders in creative fields, who are increasingly concerned about the ways generative AI models
The Indian film industry is witnessing a resurgence of thought-provoking narratives, and “The Great Departure” has emerged as a noteworthy addition to this trend. Headlined by actors Xavier Samuel and Sonal Sehgal, the film is a collaborative venture from KVR Productions, managed by Arvind Reddy, and helmed by Pierre Filmon, whose direction was previously recognized
The Kansas City Chiefs have once again secured their position in the playoffs, marking the 10th consecutive season they’ve achieved this milestone. Their recent hard-fought victory against the Las Vegas Raiders, culminating in a 19-17 score, reflects both the prowess and the poignant flaws of the reigning champions. Unlike earlier clinching victories, this one left
The world of chess is often steeped in tradition, but one player’s journey reflects the shifting realities of contemporary geopolitics. Nikita Vitiugov, a Russian grandmaster now residing in London, reveals how the complexities of international relations can creep into even the most serene of pastimes. Remarkably akin to his native St. Petersburg, London bears the
December 2024 marks the closing chapter of a remarkable trading year, with investors eagerly awaiting the final stages of what has been a historic rally across major stock indices. The upcoming month holds the potential for significant price movements driven by favorable seasonal patterns, crucial economic indicators, and earnings reports that could shape market sentiment
Crohn’s disease is a chronic inflammatory condition of the gastrointestinal tract that can significantly impact the quality of life for those affected. Patients often seek various treatments to manage their symptoms and achieve remission, yet many endure persistent symptoms despite trying standard therapies. The approval of newer biological agents, including mirikizumab (Omvoh), has sparked hope
India’s economy has recently shown a disappointing growth rate of 5.4% for the second fiscal quarter ending in September, a figure that is markedly lower than the anticipated 6.5% and notably a decline from the 6.7% growth recorded in the previous quarter. This stark contrast not only suggests that the recovery momentum might be losing